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افزایش جذب دارو ، به کمک چسباندن مادّه ی الاستیکی روی پوست | | ๑۩۞۩๑ سایت جامع مهندسی پزشکی ایران ๑۩۞۩๑

افزایش جذب دارو ، به کمک چسباندن مادّه ی الاستیکی روی پوست

مترجم هانیه بندری
کارشناسی مهندسی پزشکی گرایش بیوالکتریک دانشگاه آزاد اسلامی واحد دزفول

 

تیم تحقیقاتی دانشگاه کارولینای شمالی یک تکنولوژی جدید افزایش جذب دارو را طراحی کردند که متکی به یک اِلاستومر کِشنده و نانو ذرات پر از داروست و زمانی که پوست فشرده و کشیده می شود دارو تخلیه می گردد.

http://dezmed.com/wp-content/uploads/Captu2re.png

ایده این است که این نوع رویکرد فقط در مواردی که نیاز است دارو را از «پوست» عبور دهند استفاده می شود. برای مثال ، افرادی که آرتروز دارند قادر به گرفتن دوز مناسبی از داروی تسکین درد حتی به هنگام راه رفتن هستند. این مسیرها تشکیل شده از یک اِلاستومر که سطح آن با کپسول های کوچکی پوشیده شده و هرکدام از نانو ذرات با دارو پر می شوند. نانو ذرات به گونه ای طراحی شده اند که دارو به آرامی از کپسول هایی که روی آن قرار دارد خارج می شود. کپسول ها نشت ناپذیرند؛ اما هنگامی که فشار کافی به آن ها اعمال شود به ترکیبات اجازه می دهند که از پوست عبور کنند. این فشار از کشش اِلاستومر بدست می آید،که در اثر آن کپسول ها فشرده شده و دارو آزاد می شود. میکرونیدل ها زیر هر کپسول قرار می گیرند و به دارو اجازه می دهند که از پوست عبور کند. ترکیبی از مکانیسم ها به کپسول های نانو ذرات اجازه می دهد که با مقدار کمی دارو پر شوند و در هنگام درخواست به سرعت درون پوست آزاد شوند.

 

 

منبع خبر : www.medgadget.com

درباره ی مهندس مسعود مکوندی

کارشناس تجهیزات پزشکی - عضو مرکز پارک علم و فناوری استان خوزستان

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